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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAM
All Species:
19.09
Human Site:
S218
Identified Species:
46.67
UniProt:
P19021
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19021
NP_000910.2
973
108332
S218
A
G
E
K
V
V
N
S
D
I
S
C
H
Y
K
Chimpanzee
Pan troglodytes
XP_001136726
972
108212
S218
A
G
E
K
V
V
N
S
D
I
S
C
H
Y
K
Rhesus Macaque
Macaca mulatta
XP_001096156
907
101089
S219
A
G
E
K
V
V
N
S
D
I
S
C
H
Y
K
Dog
Lupus familis
XP_536289
1243
137222
S486
P
G
E
K
V
V
N
S
D
I
S
C
H
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
P97467
979
109029
S222
P
G
E
K
V
V
N
S
D
I
S
C
H
Y
K
Rat
Rattus norvegicus
P14925
976
108657
A223
P
G
E
K
V
V
N
A
D
I
S
C
Q
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424857
666
74100
Frog
Xenopus laevis
P12890
875
97066
T210
Y
L
S
M
S
L
N
T
V
V
P
P
G
Q
E
Zebra Danio
Brachydanio rerio
XP_699436
1010
112189
A221
P
G
K
K
V
T
N
A
D
I
A
C
T
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784943
883
95674
I214
R
N
G
E
W
T
V
I
A
K
G
S
P
K
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
91.2
70.8
N.A.
90
89.6
N.A.
N.A.
51.1
60.2
55.7
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.6
92
73.9
N.A.
94
94.2
N.A.
N.A.
59.2
74.5
70.9
N.A.
N.A.
N.A.
N.A.
49.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
80
N.A.
N.A.
0
6.6
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
0
33.3
73.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
0
20
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% D
% Glu:
0
0
60
10
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
10
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
70
0
0
0
0
0
% I
% Lys:
0
0
10
70
0
0
0
0
0
10
0
0
0
10
60
% K
% Leu:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
80
0
0
0
0
0
0
0
0
% N
% Pro:
40
0
0
0
0
0
0
0
0
0
10
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
50
0
0
60
10
0
0
0
% S
% Thr:
0
0
0
0
0
20
0
10
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
70
60
10
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _